.alpha.-ketoamide inhibitors of 20s proteasome

Details .alpha.-ketoamide inhibitors of 20s proteasome .alpha.-ketoamide inhibitors of 20s proteasome

C - Chemistry, Metallurgy

07

K

C07K 5/03 (2006.01) A61K 38/04 (2006.01) C07K 5/02 (2006.01) C07K 5/023 (2006.01) C07K 5/027 (2006.01) C07K 5/06 (2006.01) C07K 5/062 (2006.01) C07K 5/083 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2319150

.alpha.-ketoamide compounds useful for treating disorders mediated by 20S proteasome in mammals having structure (I).

Cette invention concerne des composés alpha -cétoamide convenant pour le traitement de pathologies induites chez les mammifères par le 20S protéasome et qui possèdent la structure (I).

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