.alpha.v.beta.6 integrin inhibitors

Details .alpha.v.beta.6 integrin inhibitors .alpha.v.beta.6 integrin inhibitors

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01) A61K 38/04 (2006.01) A61P 7/02 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2355874

The invention relates to novel peptides which are biologically active as ligands of .alpha.v.beta.6 integrin. Said peptides have a common structural motif, i.e. Asp Leu Xaa Leu - or in a preferred form Arg Xaa Asp Leu Xaa Xaa Leu Arg-, wherein Xaa represents any amino acid radical. The peptides according to the invention can be used as efficient .alpha.v.beta.6 integrin receptor inhibitors and consequently in the treatment of different diseases and pathologies.

L'invention concerne de nouveaux peptides biologiquement efficaces comme ligands de l'intégrine .alpha.¿v?.beta.¿6?. Ces peptides présentent tous un motif commun, à savoir - Asp Leu Xaa Xaa Leu - ou, sous une forme préférée, - Arg Xaa Asp Leu Xaa Xaa Arg -, où Xaa désigne un reste aminoacide quelconque. Les peptides selon l'invention peuvent être utilisés comme inhibiteurs efficaces du récepteur de l'intégrine .alpha.¿v?.beta.¿6? et, par conséquent, pour le traitement de différentes maladies et de différents états pathologiques.

Affiliated with

Also associated with

Rating

.alpha.v.beta.6 integrin inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with .alpha.v.beta.6 integrin inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and .alpha.v.beta.6 integrin inhibitors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1446691