C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/14 (2006.01) A61K 31/4178 (2006.01) A61K 31/4439 (2006.01) A61P 25/28 (2006.01) C07D 403/04 (2006.01) C07D 403/14 (2006.01) C07D 405/14 (2006.01) C07D 409/04 (2006.01) C07D 409/14 (2006.01) C07D 417/14 (2006.01)
Patent
CA 2613045
The present invention provides a 2-amino-5-heteroaryl-5-phenylimidazolone compound of formula I. The present invention also provides methods for the use thereof to inhibit .beta.-secretase (BACE) and treat .beta.-amyloid deposits and neurofibrillary tangles.
La présente invention concerne un composé de 2-amino-5-hétéroaryl-5-phénylimidazolone de formule I. Ladite invention concerne également des procédés d'utilisation dudit composé pour inhiber la ß-sécrétase (BACE) et traiter des dépôts ß-amyloïdes ainsi que des enchevêtrements neurofibrillaires.
Andrae Patrick Michael
Erdei James Joseph
Fobare William Floyd
Gunawan Iwan Suwandi
Malamas Michael Sotirios
Smart & Biggar
Wyeth
LandOfFree
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