Amino acid sequence evaluation system

G - Physics – 01 – N

Patent

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Details

G01N 33/00 (2006.01) G01N 33/48 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2371238

Method and apparatus for evaluating a query protein amino acid sequence with respect to an amino acid sequence motif corresponding to a target of a domain of a known protein having a known function to predict whether the query protein amino acid sequence performs the known function. In one embodiment, the prediction is performed by using a scoring system to generate a score for the query protein amino acid sequence with respect to the amino acid sequence motif. The score indicates a degree of confidence that the query protein amino acid sequence performs the known function. Several embodiments of scoring systems are described.

L'invention concerne un procédé et un appareil d'évaluation d'une séquence inconnue d'acides aminés de protéine par rapport à un motif structural de séquence d'acides aminés correspondant à une cible d'un domaine d'une protéine connue possédant une fonction connue, dans le but de prévoir si la séquence inconnue d'acides aminés de protéine possède la fonction connue. Dans un mode de réalisation, on réalise la prévision au moyen d'un système de notation de façon à obtenir une note pour la séquence inconnue d'acides aminés de protéine par rapport au motif structural de séquence d'acides aminés. La note indique le degré de certitude que la séquence inconnue d'acides aminés de protéine possède la fonction connue. L'invention concerne également plusieurs systèmes de notation.

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