Amino derivatives of b-homoandrostanes and b-heteroandrostanes

Details Amino derivatives of b-homoandrostanes and b-heteroandrostanes Amino derivatives of b-homoandrostanes and b-heteroandrostanes

C - Chemistry, Metallurgy

07

J

C07J 3/00 (2006.01) A61K 31/565 (2006.01) A61K 31/566 (2006.01) A61K 31/58 (2006.01) A61P 9/04 (2006.01) A61P 9/06 (2006.01) C07J 63/00 (2006.01)

Patent

CA 2654354

New aminoalkoxyimino derivatives at position 3 of substituted B- homoandrostanes and B-heteroandrostanes, processes for their preparation, and to pharmaceutical compositions containing them for the treatment of cardiovascular disorders, such as heart failure and hypertension. In particular compounds having the general formula (I) are described, where the radicals have the meanings described in detail in the application.

L'invention concerne de nouveaux dérivés aminoalcoxyimino en position 3 de B-homoandrostanes et B-hétéroandrostanes substitués, des procédés permettant de les préparer et des compositions pharmaceutiques les contenant pour le traitement de troubles cardio-vasculaires, tels qu'une insuffisance cardiaque et une hypertension. En particulier, des composés représentés par la formule générale (I) sont décrits, où les radicaux ont les significations décrites en détail dans la demande.

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