Aminoacyl prodrug derivatives and medicaments for the...

C - Chemistry – Metallurgy – 07 – D

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C07D 413/14 (2006.01) A61K 31/422 (2006.01) A61P 7/02 (2006.01)

Patent

CA 2642376

The present application relates to prodrug derivatives of 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxo-morpholin-4-yl)phenyl]-l,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide, methods for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, in particular of thromboembolitic disorders.

La présente invention concerne des dérivés promédicamenteux de 5-chlor-N-({(5S)-2-oxo-3-[4-(3-oxo- morpholin-4-yl)phényl]-1,3-oxazolidin-5-yl}méthyl)thiophène-2-carboxamide, des procédés de production desdits dérivés, leur utilisation dans le traitement et/ou la prophylaxie de maladies et leur utilisation dans la production de médicaments destinés au traitement et/ou à la prophylaxie de maladies, en particulier de maladies thromboemboliques.

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