C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 417/12 (2006.01) A61K 31/4184 (2006.01) A61K 31/433 (2006.01) A61K 31/437 (2006.01) A61K 31/4439 (2006.01) C07D 235/30 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 413/12 (2006.01) C07D 471/04 (2006.01) C07D 471/06 (2006.01)
Patent
CA 2536095
Novel compounds of formula (I) are disclosed, where R?1¿, R?1'¿, L, Y, m and p have the meanings given in claim 1, which are inhibitors of tyrosine kinases, in particular, TIE-2 and Raf kinases and can be used for the treatment of tumours.
L'invention concerne de nouveaux composés de la formule (I) où R?1¿, R?1'¿, L, Y, m et p ont la signification donnée dans la revendication 1. Ces nouveaux composés sont des inhibiteurs de la tyrosine-kinase, notamment de la TIE-2, et de la Raf-kinase et permettent de traiter des tumeurs.
Ackermann Karl-August
Adan Jaume
Crassier Helene
Hoelzemann Guenter
Jonczyk Alfred
Fetherstonhaugh & Co.
Merck Patent Gesellschaft Mit Beschraenkter Haftung
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