C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 451/04 (2006.01) A61K 31/46 (2006.01) C07C 229/64 (2006.01)
Patent
CA 2088702
An aminobenzoic acid derivative represented by the following general formulas (I), (I-2) or (I-3), or a pharmacologically acceptable salt thereof, which exhibits a serotinin antagonism and an acetylcholine release accelerating activity at a well-balanced activity ratio and which is efficacious as a drug for patients with gastrointestinal unidentified complaints: (see Formula I, I-2, I-3) wherein R1 represents a group such as an alkynyl or cyanoalkyl group; R2 represents a group such as an amino or acylamino group; R3 represents a halogen atom; X represents -O- or -NH-; and A represents an oxygen or sulfur atom; and R4 represents a lower alkyl or aralkyl group.
Hibi Shigeki
Hirota Kazuo
Hoshino Yorihisa
Kikuchi Kouichi
Miyazawa Shuhei
Eisai Co. Ltd.
Eisai R&d Management Co. Ltd.
G. Ronald Bell & Associates
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