C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 295/20 (2006.01) A61K 31/506 (2006.01) A61P 35/00 (2006.01) C07D 207/09 (2006.01) C07D 207/14 (2006.01) C07D 211/58 (2006.01) C07D 213/78 (2006.01) C07D 217/02 (2006.01) C07D 239/42 (2006.01) C07D 295/155 (2006.01) C07D 295/26 (2006.01) C07D 307/68 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 403/04 (2006.01) C07D 409/12 (2006.01) C07D 413/04 (2006.01) C07D 471/10 (2006.01) C12Q 1/48 (2006.01)
Patent
CA 2476583
This invention comprises the novel compounds of formula (I)wherein n, R1, R2, R3, R4, L, Q, X, Y, Z and have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
L'invention concerne des nouveaux composés de formule générale (I) dans laquelle n, R?1¿, R?2¿, R?3¿, R?4¿, L, Q, X, Y, Z et a) ont la signification indiquée dans la description, qui présentent une activité enzymatique inhibant l'histone déacetylase. L'invention concerne également leur préparation, des compositions les contenant ainsi que leur utilisation en tant que médicament.
de Winter Hans Louis Jos
Dyatkin Alexey Borisovich
Meerpoel Lieven
Van Emelen Kristof
Van Heusden Jimmy Arnold Viviane
Gowling Lafleur Henderson Llp
Janssen Pharmaceutica N.v.
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