C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 217/52 (2006.01) A61K 31/00 (2006.01) A61K 31/13 (2006.01) A61K 31/40 (2006.01) A61K 31/41 (2006.01) A61K 31/425 (2006.01) A61K 31/445 (2006.01) A61K 31/535 (2006.01) C07D 207/04 (2006.01) C07D 207/12 (2006.01) C07D 207/24 (2006.01) C07D 207/27 (2006.01) C07D 211/40 (2006.01) C07D 277/04 (2006.01) C07D 295/00 (2006.01) C07D 295/096 (2006.01) C07D 295/15 (2006.01) C07D 295/185 (2006.01) C07D 333/54 (2006.01) C07D 333/56 (2006.01) C07D 491/10 (2006.01)
Patent
CA 2326777
Aminocyclohexyl ether compounds of formula (I), or a solvate or pharmaceutically acceptable salt thereof are disclosed. In said formula, A, X and R, -R5 have the meanings given in the description. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia.
L'invention concerne des composés de formule (I) ou leur solvate ou leur sel pharmaceutiquement acceptable d'aminocyclohexyl éther qui peuvent être incorporés dans des compositions et des assortiments. Dans cette formule, A, X et R, -R¿5? sont tels que définis dans l'invention.L'invention concerne également une grande variété d'applications in vitro et in vivo pour les composés et compositions, notamment le traitement d'arythmies et la production d'analgésie ou d'anesthésie locale.
Bain Allen I.
Beatch Gregory N.
Longley Cindy J.
Plouvier Bertrand M. C.
Sheng Tao
Cardiome Pharma Corp.
Mccarthy Tetrault Llp
Nortran Pharmaceuticals Inc.
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