C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 217/60 (2006.01) A01N 37/12 (2006.01) A01N 37/44 (2006.01) A61K 31/015 (2006.01) A61K 31/19 (2006.01) A61K 31/195 (2006.01) A61K 31/215 (2006.01) A61K 31/24 (2006.01) A61P 13/04 (2006.01) C07C 229/34 (2006.01)
Patent
CA 2298493
Novel aminoethylphenoxyacetic acid derivatives represented by the general formula: (see formula I) (wherein R1 represents a hydrogen atom, a lower alkyl group or an aralkyl group; R a represents a hydrogen atom or a halogen atom; the carbon atom marked with (R) represents a carbon atom in (R) configuration; and the carbon atom marked with (S) represents a carbon atom in (S) configuration ) and pharmaceutically acceptable salts thereof, which have stimulating effects on both .beta.2- and .beta.3-adrenoceptors and are useful as agents for relieving pain and promoting the removal of calculi in urolithiasis.
Nouveaux dérivés d'acide aminoéthylphénoxyacétique de formule générale (I) et sels acceptables sur le plan pharmaceutique desdits dérivés, qui possèdent des effets de stimulation des récepteurs beta 2- et beta 3-adrénergiques et sont utiles pour réduire la douleur et favoriser la suppression des calculs dans la lithiase urinaire. Dans la formule (I), R<1> représente hydrogène, alkyle inférieur ou aralkyle, R<2> représente hydrogène ou halogéno et les atomes de carbone portant les marques (R) et (S) sont ceux qui possèdent respectivement les configurations (R) et (S).
Akahane Masuo
Hirabayashi Akihito
Mukaiyama Harunobu
Muranaka Hideyuki
Sato Masaaki
Kirby Eades Gale Baker
Kissei Pharmaceutical Co. Ltd.
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