Aminoheteroaryl compounds as protein kinase inhibitors

Details Aminoheteroaryl compounds as protein kinase inhibitors Aminoheteroaryl compounds as protein kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 213/00 (2006.01) A61K 31/496 (2006.01) A61K 31/4965 (2006.01) C07D 401/00 (2006.01) C07D 405/00 (2006.01) C07D 409/00 (2006.01) C07D 411/00 (2006.01) C07D 413/00 (2006.01) C07D 417/00 (2006.01)

Patent

CA 2517256

Aminopyridine and aminopyrazine compounds of formula (1), compositions including these compounds, and methods of their use are provided. Preferred compounds of formula 1 have activity as protein kinase inhibitors, including as inhibitors of c-MET.

L'invention concerne des composés d'aminopyridine et d'aminopyrazine représentés par la formule (1). L'invention concerne également des compositions contenant ces composés, ainsi que des procédés permettant de les utiliser. Des composés privilégiés représentés par la formule (1) ont une activité en tant qu'inhibiteurs de protéine kinase, y compris en tant qu'inhibiteurs de c-MET.

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