Aminoheteroaryl compounds as protein tyrosine kinase inhibitors

Details Aminoheteroaryl compounds as protein tyrosine kinase inhibitors Aminoheteroaryl compounds as protein tyrosine kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 213/76 (2006.01) A61K 31/4427 (2006.01) C07D 241/20 (2006.01) C07D 401/04 (2006.01) C07D 401/10 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 413/04 (2006.01) C07D 413/10 (2006.01) C07D 471/04 (2006.01) C07D 471/10 (2006.01) C07D 487/04 (2006.01) C07D 487/08 (2006.01) C07D 498/04 (2006.01)

Patent

CA 2578075

Aminoheteroaryl compounds are provided, as well as methods for their synthesis and use. Preferred compounds are potent inhibitors of the c-Met protein kinase, and are useful in the treatment of abnormal cell growth disorders, such as cancers.

L'invention concerne des composés aminohétéroaryles, ainsi que des méthodes de synthèse et d'utilisation de ces derniers. Les composés préférés sont de puissants inhibiteurs de la protéine kinase c-Met et sont utiles dans le traitement de troubles de la croissance cellulaire anormale, tels que les cancers.

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