Aminothiazole derivatives as human stearoyl-coa desaturase...

A - Human Necessities – 61 – K

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A61K 31/426 (2006.01) A61K 31/427 (2006.01) A61K 31/4439 (2006.01) A61P 3/00 (2006.01) A61P 9/12 (2006.01) A61P 17/06 (2006.01) A61P 17/10 (2006.01) A61P 19/06 (2006.01) C07D 277/82 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2618646

Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise administering to a mammal in need thereof a compound of formula (I), where V, W, R1, R2, R3 and R4 are defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.

La présente invention concerne des procédés visant à traiter une maladie ou un trouble véhiculé par la stéaroyle-CoA désaturase (SCD) chez un mammifère, de préférence un être humain, ledit procédé impliquant d'administrer à un mammifère le nécessitant un composé de formule (I), dans laquelle V, W, R1, R2, R3 et R4 sont tels que définis dans la description. L'invention concerne également des compositions pharmaceutiques comprenant les composés de formule (I).

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