An unusual retrotransposon from the yeast candida albicans

Details An unusual retrotransposon from the yeast candida albicans An unusual retrotransposon from the yeast candida albicans

C - Chemistry, Metallurgy

12

N

C12N 15/90 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C12N 9/12 (2006.01) C12N 15/10 (2006.01) C12N 15/63 (2006.01) C12N 15/81 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2287604

TCa2 is a Tyl/copia retrotransposon from the pathogenic yeast Candida albicans. In contrast to other retrotransposons it can appear as an abundant, extrachromosomal double-stranded DNA molecule, called pCal. The invention relates to the isolation and characterisation of TCa2 and pCal together with its uses for inducing random mutagenesis in a genome, as a component of a transposable element and of an expression vector.

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