Angiotensin ii antagonist imidazole derivatives, their...

Details Angiotensin ii antagonist imidazole derivatives, their... Angiotensin ii antagonist imidazole derivatives, their...

C - Chemistry, Metallurgy

07

D

C07D 403/10 (2006.01) A61K 31/415 (2006.01) C07D 233/90 (2006.01) C07D 405/14 (2006.01)

Patent

CA 2097444

Compounds of formula (I): (see formula I) [in which: R1 is hydrogen, alkyl, cycloalkyl or alkanoyl; R2 is a single bond, alkylene or alkylidene; R3 and R4 are each hydrogen or alkyl; R6 is carboxy or tetrazol-5-yl; and X is oxygen or sulfur]; and pharmaceutically acceptable salts and esters thereof are AII antagonists and can be used for the treatment and prophylaxis of hypertension and cardiovascular diseases.

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