Aniline derivatives useful as phosphodiesterase 4 inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 213/38 (2006.01) A61K 31/136 (2006.01) A61K 31/44 (2006.01) A61P 9/00 (2006.01) A61P 11/00 (2006.01) A61P 25/24 (2006.01) C07C 217/84 (2006.01) C07C 217/88 (2006.01) C07C 217/92 (2006.01) C07D 213/73 (2006.01) C07D 215/12 (2006.01) C07D 333/16 (2006.01) C07D 333/32 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07F 7/18 (2006.01)

Patent

CA 2435847

PDE4 inhibition is achieved by novel compounds, e.g., N-substituted aniline and diphenylamine analogs. The compounds of the present invention are of Formula (I): wherein R1, R2, R3 and R4 are as defined herein.

L'invention concerne de nouveaux composés de la formule (I), par exemple des analogues d'aniline N-substituté et de diphénylamine, qui inhibent PDE4. Dans ladite formule, R?1¿, R?2¿, R?3¿ et R?4¿ sont tels que définis dans le mémorandum descriptif.

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