Animal cells and processes for the replication of influenza...

C - Chemistry – Metallurgy – 12 – N

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C12N 7/00 (2006.01) A61K 39/145 (2006.01) C12Q 1/70 (2006.01) G01N 33/569 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2250714

Animal cells are described which can be infected by influenza viruses and which are adapted to growth in suspension in serum-free medium. Processes for the replication of influenza viruses in cell culture using these cells are furthermore described, as well as vaccines which contain the influenza viruses obtainable by the process or constituents thereof.

L'invention se rapporte à des cellules animales qui peuvent être infectées par les virus de la grippe et qui sont adaptées à être cultivées en suspension dans un milieu dépourvu de sérum. Des procédés destinés à la réplication de virus de la grippe dans une culture cellulaire et faisant appel à ces cellules sont également décrits, ainsi que des vaccins contenant les virus de la grippe pouvant être obtenus par ce procédé ou des parties constitutives de ceux-ci.

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