Antheilmintic milbemycin analogs of novel microorganisms

Details Antheilmintic milbemycin analogs of novel microorganisms Antheilmintic milbemycin analogs of novel microorganisms

C - Chemistry, Metallurgy

07

D

C07D 315/00 (2006.01) A01N 45/00 (2006.01) A61K 31/365 (2006.01) C12N 1/20 (2006.01) C12P 17/08 (2006.01)

Patent

CA 2067723

162/DLR85 18307IA TITLE OF THE INVENTION NOVEL ANTHELMINTIC MILBEMYCIN ANALOGS OF NOVEL MICROORGANISMS ABSTRACT OF THE DISCLOSURE There is disclosed a series of macrolides isolated from the fermentation broth of microorganisms identified as MA-6825, MA-6864 and MA-6865. The structure of the novel compounds isolated from the microorganisms is presented based upon analytical studies. The compounds are highly potent antiparasitic, insecticidal, and anthelmintic agents and are related to the class of macrolides known as milbemycins. Compositions for such uses are also disclosed.

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