Anti-cancer drugs comprising platinum complexes

Details Anti-cancer drugs comprising platinum complexes Anti-cancer drugs comprising platinum complexes

A - Human Necessities

61

K

167/119

A61K 39/395 (2006.01) A61K 47/48 (2006.01)

Patent

CA 1224718

ABSTRACT: There are provided anti-tumor agents comprising as active ingredient platinum complexed directly or via dextran- amine moieties to an anti-tumor immunoglobulin. These are prepared by reacting an anti-tumor immunoglobulin or such immunoglobulin coupled to a dextran-amine with a platinum salt. Immunoglobulins having a specific binding activity towards certain types of cancer cells can be used. Immuno- globulins specific for ovarian or testicular carcinoma or for renal adenocarcinoma complexed directly or via dextran-amine moieties with platinum are effective agents for the treatment of these malignancies.

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