Anti-cd18 antibodies for use against stroke

Details Anti-cd18 antibodies for use against stroke Anti-cd18 antibodies for use against stroke

A - Human Necessities

61

K

A61K 39/395 (2006.01) C07K 16/28 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2242414

A method for improving clinical outcome in focal ischemic stroke in a mammal by increasing cerebral blood flow and/or reducing infarct size is described which involves administering an effective amount of an anti-CD18 antibody to the mammal, in the absence of removal of the arterial obstruction.

Cette invention se rapporte à un procédé permettant d'améliorer les résultats cliniques s'agissant de l'attaque ischémique focale chez un mammifère, par accroissement du flux sanguin cérébral et/ou réduction de la taille de l'infarctus cérébral. Ledit procédé consiste à administrer audit mammifère une quantité efficace d'un anticorps dirigé contre le CD18, et ce sans retrait de l'obstruction artérielle.

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