Anti-coagulant properties of macrocyclic compounds and...

C - Chemistry – Metallurgy – 07 – C

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C07C 309/43 (2006.01) A61K 31/18 (2006.01) A61K 31/185 (2006.01) A61K 31/19 (2006.01) A61K 31/215 (2006.01) A61K 31/255 (2006.01) A61K 31/66 (2006.01) A61K 31/765 (2006.01) A61K 31/795 (2006.01) A61K 31/80 (2006.01) C07C 59/52 (2006.01) C07C 65/105 (2006.01) C07C 309/11 (2006.01) C07C 309/24 (2006.01) C07C 309/42 (2006.01) C07C 309/44 (2006.01) C07C 309/50 (2006.01) C07C 309/58 (2006.01) C07C 309/60 (2006.01) C07C 309/73 (2006.01) C07C 309/75 (2006.01) C07C 309/77 (2006.01) C07C 311/29 (2006.01) C07C 311/37

Patent

CA 2100676

2100676 9212708 PCTABS00014 A pharmaceutical composition is disclosed for use in inhibiting blood coagulation in a human subject. The composition includes a macrocyclic compound composed of aryl ring subunits connected one to another by ring-attached bridge linkages, and containing sulfonic acid-derived substituents carried on non-bridge atoms of the subunits, carried in a pharmaceutically acceptable carrier. Also disclosed are novel macrocyclic compounds.

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