Anti-retroviral analysis by mass spectrometry

G - Physics – 01 – N

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G01N 33/15 (2006.01) B01D 59/44 (2006.01) G01N 33/48 (2006.01)

Patent

CA 2521048

Methods for the simultaneous or sequential analysis and quantification of a plurality of antiretroviral analytes in a complex biological matrix by mass spectrometry are disclosed. The methods require minimal sample size, minimal preparation time and allow for rapid through-put. The system is particularly useful in therapeutic drug monitoring.

L~invention concerne des procédés pour l~analyse et la quantification simultanées ou séquentielles d'une pluralité d~analytes anti-rétroviraux dans une matrice biologique complexe par spectrométrie de masse. Ces procédés nécessitent un nombre d~échantillons minimal, un temps de préparation minimal et permettent un débit rapide. Le système est particulièrement utile pour la pharmacovigilance thérapeutique.

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