Antibiotic compounds

Details Antibiotic compounds Antibiotic compounds

C - Chemistry, Metallurgy

07

D

260/100, 167/187

C07D 501/46 (2006.01) A61K 31/535 (2006.01) A61K 31/545 (2006.01) C07D 209/48 (2006.01) C07D 275/06 (2006.01) C07D 463/00 (2006.01) C07D 491/04 (2006.01) C07D 501/00 (2006.01) C07D 513/04 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2022664

A B S T R A C T ANTIBIOTIC COMPOUNDS Cephalosporin antibiotics having a 3-position substituent of the formula: Image are described, wherein X is -CO-, -SO2- or -COCH2-; Y is -CO-, -SO2- or -CH2-; O is a benzene, pyridine or naphthalene ring, R1 and R2 are ortho with respect to each other and are independently hydroxy or of the formula O-M wherein M is a moiety and the O-M bond is cleavable in vivo and ring O may be further substituted by a variety of atoms and groups. Processes for their preparation and use are described.

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