C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/18 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) C07K 16/30 (2006.01) C12N 15/13 (2006.01)
Patent
CA 2545756
In accordance with the present invention, there are provided fully human monoclonal antibodies against secretory leukocyte protease inhibitor (SLPI) and antigen binding fragments thereof. Nucleotide sequences encoding and amino acid sequences comprising heavy and light chain immunoglobulin molecules are provided. The invention provides antibodies and antigen-binding fragments thereof specifically bind to SLPI; act to neutralize SLPI activity; and can modulate SLPI effects.
La présente invention concerne des anticorps monoclonaux entièrement humains dirigés contre l'inhibiteur de la protéase des leucocytes sécréteurs (SLPI) ainsi que des fragments de liaison à l'antigène de ces anticorps. Cette invention concerne également le codage de séquences nucléotidiques ainsi que des séquences d'acides aminés comprenant des molécules d'immunoglobuline à chaînes lourdes et légères. Cette invention concerne en outre des anticorps et des fragments de liaison à l'antigène de ces anticorps qui se lient spécifiquement à l'inhibiteur SLPI, qui agissent pour neutraliser l'activité de l'inhibiteur SLPI et qui peuvent moduler les effets de l'inhibiteur SLPI.
Chui Daniel
Gallo Michael L.
Gulshan Ara
Larochelle William J.
Zhong Haihong
Abgenix Inc.
Curagen Corporation
Ridout & Maybee Llp
LandOfFree
Antibodies against secretoryleukocyte protease inhibitor does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Antibodies against secretoryleukocyte protease inhibitor, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antibodies against secretoryleukocyte protease inhibitor will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1551061