C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/13 (2006.01) A01H 5/00 (2006.01) A01N 63/02 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/435 (2006.01) C07K 16/18 (2006.01) C12N 15/12 (2006.01) C12N 15/82 (2006.01)
Patent
CA 2241977
The invention concerns antibodies directed against an antigenic subventral salivary protein of a cyst nematode, e.g. of the genera Heterodera, Globodera and Punctodera, or at an immunogenic part or equivalent thereof, said antigenic protein having an amino acid of 30-50 kDa and having an isoelectric point (pI) of about 6.8 to 8.7. Furthermore provided are expression systems comprising at least a nucleotide sequence encoding an antibody or antibody fragment against a cyst nematode salivary protein, and a sequence regulating expression of said nucleotide sequence, for transforming plants so as to protect them against cyst nematodes.
Anticorps dirigés contre une protéine salivaire sous-ventrale antigénique d'un nématode kystique, par exemple des genres Heterodera, Globodera et Punctodera, ou encore contre sa partie immunogène ou son équivalent, ladite protéine antigénique ayant un acide aminé de 30 à 50 kDa, et un point isoélectrique (pI) compris entre 6,8 et 8,7 environ. En outre, on a prévu des systèmes d'expression comportant au moins une séquence nucléotidique codant un anticorps ou fragment anticorpal dirigé contre une protéine salivaire de nématode kystique, ainsi qu'une séquence régulant l'expression de ladite séquence nucléotidique, pour la transformation des plantes en vue de leur protection contre les nématodes kystiques.
Bakker Jacob
Schots Arjen
Stiekema Wilhelmus Johannes
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Landbouwuniversiteit Wageningen
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