C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/13 (2006.01) A61K 39/395 (2006.01) C07K 16/28 (2006.01) C12N 15/62 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2328606
The invention relates to antibodies which bind to the CD23 (FC.epsilon.RII) type II molecule particularly altered antibodies including antibodies which bind to the CD23 (FC.epsilon.RII) type II molecule characterised by an affinity constant equal to or greater than 1x109 Ka Mo1-1, the preparation of such antibodies, pharmaceutical compositions which contain such antibodies and their use in therapy particularly in the treatment of autoimmune and inflammatory disorders.
La présente invention concerne des anticorps qui se lient à la molécule CD23 (FC.epsilon.RII) de type II, en particulier des anticorps modifiés comprenant des anticorps qui se lient à la molécule CD23 (FC.epsilon.RII) de type II et qui sont caractérisés par une affinité constante supérieure ou égale à 1x10?9¿ Ka Mo1?-1¿. L'invention se rapporte également à la préparation de ces anticorps, à des compositions pharmaceutiques contenant ces anticorps et à leur utilisation en thérapie, en particulier dans le traitement des affections auto-immunes et inflammatoires.
Bonnefoy Jean-Yves Marcel Paul
Crowe Scott James
Ellis Jonathan Henry
Rapson Nicholas Timothy
Shearin Jean
Glaxo Group Limited
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
LandOfFree
Antibodies to cd23, derivatives thereof, and their... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Antibodies to cd23, derivatives thereof, and their..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antibodies to cd23, derivatives thereof, and their... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1739415