Antibodies to the fuel oxygenate mtbe and use thereof in...

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 16/44 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2531103

Immunoassay of methyl tert-butyl ether (MTBE) and related fuel oxygenates and their breakdown products is performed using a monoclonal antibody produced using a hapten with a CH3-O-C(CH3)2-CH2-moiety, preferably CH3-O-C(CH3)2 - (CH2)3-CH(CH3)-CH2-CHO conjugated to a carrier protein.

Selon l'invention, un essai immunologique de méthyl <u>tert</u>-butyl éther (MTBE) et de carburants oxygénés associés, ainsi que de leurs produits de dégradation, est réalisé au moyen d'un anticorps monoclonal produit au moyen d'un haptène avec un groupe CH¿3?-O-C(CH¿3?)¿2?-CH2, de préférence CH¿3?-O-C(CH¿3?)¿2? -(CH¿2?)¿3?-CH(CH¿3?)-CH¿2?-CHO conjugué à une protéine de support.

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