Antibody preparation and process for its manufacture and use

G - Physics – 01 – N

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167/139, 167/44

G01N 33/531 (2006.01) A61K 39/395 (2006.01) C07D 233/54 (2006.01) C07K 16/18 (2006.01)

Patent

CA 1273572

Abstract Antibody preparation containing antibodies or fragments or derivatives thereof which possess biospecific immunotype affinity to a 4-(2-aminoethyl)-imidazolyl group bound to an aliphatic carbon atom; process for manufacturing said preparation; and process for using it. In said manufacturing process, cells capable of expressing an antibody having a specificity pursuant to the invention are caused in a manner known per se to express said anti- body, whereupon said antibody can be isolated and purified in a manner known per se. The antibody preparation of this invention is used as a reactant in immunological assay methods for inter alia histamine and/or methyl histamine determinations.

500297

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