C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 19/00 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) C07K 16/30 (2006.01) C12N 15/62 (2006.01) C12N 15/63 (2006.01)
Patent
CA 2754764
The present invention includes compositions and methods for the expression, secretion and use of novel compositions for use as, e.g., vaccines and antigen delivery vectors, to delivery antigens to antigen presenting cells. In one embodiment, the vector is an anti-CD40 antibody, or fragments thereof, and one or more antigenic peptides linked to the anti-CD40 antibody or fragments thereof, including humanized antibodies.
L'invention porte sur des compositions et méthodes d'expression, sécrétion et utilisation de nouvelles compositions utilisables par exemple en tant que vaccins et vecteurs de délivrance d'antigènes à des cellules comportant des antigènes. Dans une exécution, le vecteur est: un anticorps anti-CD40, ou l'un de ses fragments, ou un ou plusieurs peptides antigènes liés à l'anticorps anti-CD40 ou à l'un de ses fragments, dont des anticorps humanisés.
Akagawa Keiko
Banchereau Jacques F.
Flamar Anne-Laure
Klucar Peter
Montes Monica
Baylor Research Institute
Shapiro Cohen
LandOfFree
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