Antimicrobial and anti-inflammatory peptides

Details Antimicrobial and anti-inflammatory peptides Antimicrobial and anti-inflammatory peptides

C - Chemistry, Metallurgy

07

K

C07K 7/08 (2006.01) A61K 38/10 (2006.01) A61P 31/04 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2457885

Antimicrobial and/or anti-inflammatory peptide compositions and therapeutic uses thereof are provided. The peptides and analogs or derivatives thereof may be used as an antimicrobial agent and/or as an anti-inflammatory agent. In certain embodiments, the peptides are cationic peptides. The peptides are useful for the treatment of inflammatory diseases, such as microorganism- caused infections, acne, and psoriasis. The peptides and peptide formulations may be used topically or parenterally.

L'invention concerne des compositions antimicrobiennes et/ou anti-inflammatoires, ainsi que leurs utilisations thérapeutiques. Les peptides et les analogues ou les dérivés de ces compositions peuvent être utilisés en tant qu'agents antimicrobiens et/ou agents anti-inflammatoires. Dans certains modes de réalisation, les peptides sont des peptides cationiques. Ces peptides sont utiles dans le traitement des maladies inflammatoires, telles que les infections causées par des micro-organismes, l'acné et le psoriasis. Les peptides et les préparations peptidiques selon l'invention peuvent être utilisés de manière topique ou parentérale.

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