Antimicrobial peptides

A - Human Necessities – 61 – K

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Details

A61K 38/17 (2006.01) A61K 31/04 (2006.01) A61P 31/10 (2006.01)

Patent

CA 2574959

The present invention relates to a group of peptidic compounds which have antimicrobial activity. The compounds also have affinity for toxins and especially for bacterial toxins, such as lipopolysaccharide or lipoteichoic acid. The compounds can be used to manufacture medicaments useful for the treatment of bacterial or fungal infections. The medicaments may be administered systemically or locally.

L'invention concerne un groupe de composés peptidiques qui présentent une activité anti-microbienne. Les composés présentent également une affinité aux toxines et en particulier des toxines bactériennes, tels que des lipopolysaccharides ou de l'acide lipoteichoïque. Les composés de l'invention peuvent être utilisés pour fabriquer des médicaments utilisés dans le traitement des infections bactériennes ou fongiques. Les médicaments peuvent être administrés systématiquement ou localement.

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