Antisense composition and method for inhibition of mirna...

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Details

A61K 31/7088 (2006.01) A61K 31/7125 (2006.01) A61P 3/06 (2006.01) A61P 9/00 (2006.01) A61P 35/00 (2006.01) C07H 21/04 (2006.01) C12N 15/11 (2006.01)

Patent

CA 2661765

The present disclosure relates to compounds and methods for inhibiting the formation of miRNAs that inhibit translation of one or more identified proteins. The compounds comprise antisense oligonucleotides targeting the ph-miRNA precursor of miRNAs.

La présente invention concerne des composés et des procédés permettant d'inhiber la formation d'ARNmi qui bloquent la translation d'une ou de plusieurs protéines identifiées. Les composés comprennent des oligonucléotides antisens ciblant le précurseur ARNmi-ph des ARNmi.

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