C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 21/04 (2006.01) A61K 31/7125 (2006.01) A61K 48/00 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2513398
New antisense oligonucleotide compounds, RX-0047 and RX-0149, inhibit expression of HIF-1 and also induce cytotoxicity in several cancer cell lines.
L'invention concerne de nouveaux composés oligonucléotidiques anti-sens, RX-0047 et RX-0149, qui inhibent l'expression du HIF-1 et induisent également une cytotoxicité dans plusieurs lignées cellulaires cancéreuses.
Ahn Chang-Ho
Bok Lee Young
Jiang Xiaoming
Mao Lingjun
Yoon Heejeong
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Rexahn Corporation
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