C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 333/58 (2006.01) A61K 31/381 (2006.01) A61K 31/40 (2006.01) A61K 31/4025 (2006.01) A61K 31/41 (2006.01) A61K 31/4178 (2006.01) A61K 31/422 (2006.01) A61K 31/44 (2006.01) A61K 31/4439 (2006.01) A61K 31/454 (2006.01) A61K 31/4545 (2006.01) A61K 31/495 (2006.01) A61K 31/497 (2006.01) A61K 31/535 (2006.01) A61K 31/5377 (2006.01) A61K 31/55 (2006.01) C07D 295/112 (2006.01) C07D 307/81 (2006.01) C07D 333/56 (2006.01) C07D 333/62 (2006.01) C07D 333/64 (2006.01) C07D 333/66 (2006.01) C07D 405/00 (2006.01) C07D
Patent
CA 2236007
This application relates to the use as thrombin inhibitors, coagulation inhibitors and thromboembolic disorder agents of diamines of formula (I) as defined herein. It also provides novel compounds of formula (I), processes and intermediates for their preparation, and pharmaceutical formulations comprising the novel compounds of formula (I).
La présente invention concerne l'utilisation, comme inhibiteurs de thrombine, inhibiteurs de coagulation et agents destinés aux désordres de la thromboembolie, de diamines de formule I telle qu'elle est définie dans la description. L'invention concerne aussi des composés nouveaux de formule I, des procédés et des produits intermédiaires pour leur préparation, et des formulations pharmaceutiques comprenant les composés nouveaux de formule I.
Bastian Jolie Anne
Chirgadze Nickolay Yuri
Denney Michael Lyle
Foglesong Robert James
Harper Richard Waltz
Eli Lilly And Company
Gowling Lafleur Henderson Llp
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