A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 45/06 (2006.01) A61K 38/12 (2006.01)
Patent
CA 2540108
The present invention relates to an antitumor agent containing a histone deacetylase inhibitor and a topoisomerase II inhibitor in combination, and an enhancer of antitumor effect of topoisomerase II inhibitor, which contains a histone deacetylase inhibitor as an active ingredient. The present invention provides an antitumor agent having superior antitumor activity, which is associated with a fewer side effects.
La présente invention concerne, d'une part, un agent antitumoral contenant un inhibiteur de l'histone déacétylase et un inhibiteur de la topoisomérase II combinés, et, d'autre part, un amplificateur de l'effet antitumoral de l'inhibiteur de la topoisomérase II qui renferme un inhibiteur de l'histone déacétylase, en tant qu'ingrédient actif. Cette invention a aussi trait à un agent antitumoral possédant une activité antitumorale supérieure associée à des effets secondaires moindres.
Naoe Yoshinori
Sasakawa Yuka
Astellas Pharma Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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