Antitumor agent effect enhancer containing il-6 antagonist

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/395 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2209124

The present invention discloses an effect enhancer for antitumor agents, examples of which include platinum compounds such as cisplatin and carboplatin, and mitomycin C, that contains interleukin-6 (IL-6) antagonist, examples of which include antibody to IL-6, antibody to IL-6 receptor, and antibody to gp130 protein.

L'invention concerne un potentialisateur destiné à des agents antitumoraux, par exemple à des composés du platine, tels que cisplatine et carboplatine, mitomycine C, etc. Ce potentialisateur comprend un antagoniste de l'interleukine 6 (IL-6) par exemple un anticorps dirigé contre l'IL-6, un anticorps dirigé contre le récepteur de l'IL-6, un anticorps dirigé contre la protéine gp130, etc.

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