C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 493/18 (2006.01) A61K 31/357 (2006.01) A61P 35/00 (2006.01) C07D 311/00 (2006.01) C07D 323/00 (2006.01) C07D 493/22 (2006.01)
Patent
CA 2633543
The invention relates to novel antitumor compounds of general formula (see formula I) as well as their corresponding pharmaceutically acceptable salts, derivatives, prodrugs and stereoisomers. These compounds can be obtained by isolating a sponge from family Theonellidae, genus Theonella and species swinhoei, and forming derivatives from the isolated compounds. These compounds have cytotoxic activity and can be used for the treatment of the cancer.
L'invention concerne de nouveaux composés antitumoraux de formule générale (I), ainsi que leurs sels pharmaceutiquement acceptables, dérivés, promédicaments et stéréoisomères. Il est possible d'obtenir des composés en isolant une éponge de la famille Theonellidae, genre Theonella et espèce swinhoei et en formant des dérivés à partir des composés isolés. Lesdits composés présentent une activité cytotoxique et sont utiles dans le traitement du cancer.
Coello Molinero Laura
Cuevas Marchante Maria Del Carmen
Fernandez Rodriguez Rogelio
Francesch Solloso Andres
Martin Lopez Ma Jesus
Pharma Mar S.a.
Smart & Biggar
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