Antiviral phosphonic acid derivatives of purine analogues

Details Antiviral phosphonic acid derivatives of purine analogues Antiviral phosphonic acid derivatives of purine analogues

C - Chemistry, Metallurgy

07

F

C07F 9/547 (2006.01) A61K 31/675 (2006.01) C07F 9/6561 (2006.01)

Patent

CA 2132303

2132303 9319075 PCTABS00025 Compounds of formula (I), or a pharmaceutically acceptable salt thereof wherein X is -CH2O, -CH2 or -CH(CH2OR6)O where R6 is hydrogen or acyl; Y is O or S; R1 is hydroxy or amino; R2 is amino or hydrogen; R3 is hydrogen or, when X is CH2O and Y is O, R3 may be CH2OR7 where R7 is hydrogen or acyl; and R4 and R5 are both phenyl, 4-bromophenyl, 4-methylphenyl, 4-methoxyphenyl, 2-acetoxyphenyl or 2-methylphenyl; and their pharmaceutical use in the treatment of viral diseases.

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