Apparatus for capillary electrophoresis

Details Apparatus for capillary electrophoresis Apparatus for capillary electrophoresis

B - Operations, Transporting

01

D

204/171, 204/171

B01D 57/02 (2006.01) G01N 27/447 (2006.01) G01N 27/453 (2006.01)

Patent

CA 2004570

12 APPARATUS FOR CAPILLARY ELECTROPHORESIS ABSTRACT OF THE DISCLOSURE A capillary tube for use in high performance capillary electrophoresis is enclosed in a cartridge of generally planar configuration, formed by two flat plates joined together along raised edges to define a shallow enclosed chamber to retain the looped capillary tube, the plates having aligned windows between which a segment of the capillary tube passes, thereby forming a light path for zone detection. The termini of the capillary are embedded in fittings extending from the exterior of the cartridge, which mate with complementary fittings on inlet and outlet blocks which contain buffer reservoirs with controlled hydrostatic heads. The inlet block is specially equipped with ducts and fittings to permit filling of the capillary, injection of the sample into the capillary, changing of the solution in the buffer reservoir, and flushing out of the entire block without disconnecting the block from the capillary cartridge. By securing the cartridge containing the capillary tube into its holder, the capillary tube is correctly aligned in the detector light path.

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