Aptamers labelled with gallium-68

A - Human Necessities – 61 – K

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

A61K 51/08 (2006.01) A61K 51/04 (2006.01) A61P 35/00 (2006.01) C12N 15/11 (2006.01)

Patent

CA 2662693

This invention relates to novel nucleotide-based compounds, methods of making radiolabeled compounds and use of such compounds for diagnostic imaging. Provided are compounds according to Formula (I): A - B - L - C, wherein A stands for an aptamer, B is absent or stands for a bridging structure, L is a linker, and C is a metal ion chelator. All substituents are defined in detail in the description. Preferred embodiments of said compounds bind to Tenascin-C.

La présente invention concerne de nouveaux composés à base de nucléotide, des procédés de fabrication de composés radiomarqueurs et l'utilisation de tels composés en imagerie diagnostique. La présente invention concerne des composés de formule (I): A - B - L - C, dans laquelle A représente un aptamère, B est absent ou représente une structure pontée, L représente un lieur et C représente un chélateur d'ion métallique. Tous les substituants sont définis en détail dans la description. Les modes de réalisation préférés desdits composés se lient à la Ténascine-C.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Aptamers labelled with gallium-68 does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Aptamers labelled with gallium-68, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Aptamers labelled with gallium-68 will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1779676

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.