A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/661 (2006.01) A61K 47/02 (2006.01) A61K 47/18 (2006.01) A61P 23/00 (2006.01)
Patent
CA 2662643
The present invention is directed to aqueous based formulations of water-soluble prodrugs of propofol. The formulations comprise in aqueous medium an effective amount of the water-soluble prodrug of propofol in the absence of an antioxidant. The formulations are particularly useful as intravenous injections. The formulations preferably are buffered to a pH suitable for minimizing degradation of the prodrug during storage. The formulations can be prepared without the use of harmful co-solvents or surfactants and are stable at room temperature over extended periods of time.
La présente invention concerne des formulations pharmaceutiques à base aqueuse de promédicaments hydrosolubles du propofol. Les formulations comprennent, dans un milieu aqueux, une quantité efficace du promédicament hydrosoluble du propofol en absence d'oxidant. Les formulations sont particulièrement utiles en tant qu'injections intraveineuses. Les formulations sont de préférence tamponnées à un pH approprié pour minimiser la dégradation du promédicament pendant le stockage. Les formulations peuvent être préparées sans utiliser de co-solvants ou de tensioactifs nocifs et sont stables à température ambiante pendant des durées prolongées.
Dordunoo Stephen
Keller David
Patel Kanaiyalal R.
Eisai Corporation Of North America
Eisai Inc.
Smart & Biggar
LandOfFree
Aqueous based pharmaceutical formulations of water-soluble... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Aqueous based pharmaceutical formulations of water-soluble..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Aqueous based pharmaceutical formulations of water-soluble... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1518122