Aqueous solution inclusion complexes of benzothiophene...

A - Human Necessities – 61 – K

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A61K 47/40 (2006.01) A61K 31/38 (2006.01) A61K 31/381 (2006.01) A61K 31/40 (2006.01) A61K 31/445 (2006.01) A61K 47/48 (2006.01)

Patent

CA 2137533

The present invention provides aqueous inclusion complexes of certain known benzothiophene compounds, particularly Raloxifene, and water soluble cyclodextrins. Also provided are pharmaceutical compositions of such inclusion complexes, and methods of using these complexes for inhibiting bone loss and reducing serum cholesterol in mammals.

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