Aryl- and heteroarylcarbonyl derivatives of benzomorphanes...

Details Aryl- and heteroarylcarbonyl derivatives of benzomorphanes... Aryl- and heteroarylcarbonyl derivatives of benzomorphanes...

C - Chemistry, Metallurgy

07

D

C07D 221/26 (2006.01) A61K 31/439 (2006.01) A61P 3/10 (2006.01) C07D 401/06 (2006.01) C07D 401/14 (2006.01) C07D 403/06 (2006.01) C07D 405/06 (2006.01) C07D 413/06 (2006.01) C07D 413/14 (2006.01) C07D 417/06 (2006.01) C07D 451/06 (2006.01) C07D 471/08 (2006.01) C07D 498/08 (2006.01)

Patent

CA 2704628

The present invention relates to compounds defined by formula (1), wherein the groups R1 to R3, X, in, n and o are defined as in claim 1, possessing valuable pharmacological activity. Particularly the compounds are inhibitors of 11 .beta.-hydroxysteroid dehydrogenase (HSD) 1 and thus are suitable for treatment and prevention of diseases which can be influenced by inhibition of this enzyme, such as metabolic diseases, in particular diabetes type 2, obesity and dyslipidemia.

La présente invention concerne des composés définis par la formule (I), dans laquelle les groupes R1 à R3, X, m, n et o sont tels que définis dans la revendication 1, possédant une importante activité pharmacologique. En particulier, les composés sont des inhibiteurs de la 11-ß-hydroxystéroïde déshydrogénase (HSD) 1 et sont ainsi appropriés pour le traitement et la prévention de maladies qui peuvent être influencées par l'inhibition de cette enzyme, telles que des maladies métaboliques, en particulier le diabète de type 2, l'obésité et la dyslipidémie.

Affiliated with

Also associated with

Rating

Aryl- and heteroarylcarbonyl derivatives of benzomorphanes... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Aryl- and heteroarylcarbonyl derivatives of benzomorphanes..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Aryl- and heteroarylcarbonyl derivatives of benzomorphanes... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1916206