Aryl furan derivatives as pde iv inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 307/42 (2006.01) A61K 31/34 (2006.01) C07D 307/38 (2006.01) C07D 307/46 (2006.01) C07D 307/54 (2006.01) C07D 307/56 (2006.01) C07D 307/64 (2006.01) C07D 307/66 (2006.01) C07D 405/04 (2006.01) C07D 405/06 (2006.01) C07D 405/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01) C07D 473/38 (2006.01) C07F 7/08 (2006.01)

Patent

CA 2305413

The invention encompasses the novel compound of Formula (I) useful in the treatment of diseases, including asthma, by raising the level of cyclic adenosine-3',5'-monophosphate (cAMP) through the inhibition of phosphodiesterase IV (PDE IV). The invention also encompasses certain pharmaceutical compositions and methods for treatment of diseases by inhibition of PDE IV, resulting in an elevation of cAMP, comprising the use of compounds of Formula (I).

L'invention concerne le nouveau composé de formule (I) utile dans le traitement de maladies, notamment de l'asthme, par l'élévation du taux d'adénosine-3',5'-monophosphate cyclique (cAMP) grâce à l'inhibition de la phosphodiestérase IV (PDE IV). L'invention concerne également certaines compositions pharmaceutiques et des méthodes pour traiter des maladies par l'inhibition de PDE IV, entraînant une élévation de cAMP consistant à utiliser les composés de formule (I).

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