C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/12 (2006.01) A61K 31/44 (2006.01) A61K 31/47 (2006.01) A61P 25/00 (2006.01) C07D 403/14 (2006.01) C07D 405/12 (2006.01) C07D 487/04 (2006.01)
Patent
CA 2593266
This invention provides novel aryl piperazine derivatives having medical utility, in particular as modulators of dopamine and serotonin receptors, preferably the D3, D2-like and 5-HT2 receptor subtypes, and in particular useful for the treatment of neuropsychiatric disorders incl. schizophrenia. Formula (I) an enantiomer thereof or a mixture of its enantiomers, or a pharmaceutically acceptable salt thereof, or an N-oxide thereof.
L'invention concerne de nouveaux dérivés d'aryle pipérazine possédant une utilité médicale, en particulier, en tant que modulateurs des récepteurs de dopamine et de sérotonine, de préférence, les sous-types des récepteurs D3, analogue à D2 et 5-HT2, ces dérivés étant, en particulier utiles, pour traiter des troubles neuropsychiatriques, y compris la schizophrénie.
Butini Stefania
Campiani Giuseppe
de Angelis Meri
Fattorusso Caterina
Franceschini Silvia
Campiani Giuseppe
Mccarthy Tetrault Llp
Universita Degli Studi Di Siena
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