Aryl thiophene derivatives as pde iv inhibitors

Details Aryl thiophene derivatives as pde iv inhibitors Aryl thiophene derivatives as pde iv inhibitors

C - Chemistry, Metallurgy

07

D

C07D 409/12 (2006.01) A61K 31/38 (2006.01) C07D 213/00 (2006.01) C07D 239/00 (2006.01) C07D 241/00 (2006.01) C07D 333/00 (2006.01) C07D 333/16 (2006.01) C07D 333/24 (2006.01) C07D 409/04 (2006.01) C07D 409/14 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2305414

The invention encompasses the novel compound of Formula (I) useful in the treatment of diseases, including asthma, by raising the level of cyclic adenosine-3',5'-monophosphate (cAMP) through the inhibition of phosphodiesterase IV (PDE IV). The invention also encompasses certain pharmaceutical compositions and methods for treatment of diseases by inhibition of PDE IV, resulting in an elevation of cAMP, comprising the use of compounds of Formula (I).

L'invention concerne un nouveau composé de formule (I) servant dans le traitement de maladies telles que l'asthme. Ce composé élève le taux de l'adénosine-3',5'-monosphophate cyclique (cAMP) par inhibition de la phosphodiestérase IV (PDE IV). L'invention concerne également l'utilisation des composés de formule (I) dans certaines compositions pharmaceutiques et dans des méthodes de traitement de maladies par inhibition de la PDE IV, et par conséquent élévation du taux de cAMP.

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