Arylmethyl-carbonylamino-thiazole derivatives and their use...

Details Arylmethyl-carbonylamino-thiazole derivatives and their use... Arylmethyl-carbonylamino-thiazole derivatives and their use...

C - Chemistry, Metallurgy

07

D

C07D 277/46 (2006.01) A61K 31/426 (2006.01) A61K 31/427 (2006.01) A61K 31/4439 (2006.01) A61K 31/454 (2006.01) A61K 31/497 (2006.01) A61P 35/00 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2381097

2-amino-1.3-thiazole derivatives represented by formula (I) or (II): where R, R1, R2 and R3 are as defined herein, or pharmaceutically acceptable salts thereof, are useful in, for example, the treatment of cancer, cell proliferative disorders, Alzheimer's disease, viral infections, auto-immune diseases or neurodegenertive diseases.

La présente invention concerne des dérivés de 2-amino-1,3-thiazole représentés par la formule (I) ou par la formule (II) dans lesquelles R, R1, R2 et R3 sont tels que définis ci-dessus, ou des sels pharmaceutiquement acceptables de ces derniers, qui sont utilisés, par exemple, dans le traitement du cancer, dans les troubles de la prolifération cellulaire, dans la maladie d'Alzheimer, dans les infections virales, dans les maladies autoimmunes ou dans les maladies neurodégénératives.

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