Arylmethylamine derivatives for use as tryptase inhibitors

Details Arylmethylamine derivatives for use as tryptase inhibitors Arylmethylamine derivatives for use as tryptase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 211/16 (2006.01) C07D 211/26 (2006.01) C07D 211/32 (2006.01) C07D 211/58 (2006.01) C07D 401/06 (2006.01) C07D 401/10 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 405/06 (2006.01) C07D 405/10 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 409/06 (2006.01) C07D 409/14 (2006.01) C07D 411/06 (2006.01) C07D 413/10 (2006.01) C07D 413/14 (2006.01) C07D 417/06 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01) C07D 495/04 (2006.01) C07D 513/04 (2006.01)

Patent

CA 2409827

Provided herein are compounds of formula (I) wherein R1-4, n and Ar are as defined in claim 1, and their pharmaceutical compositions. These compounds are tryptase inhibitors and may be used in the treatment of e.g. asthma and inflammatory diseases.

Cette invention concerne des composés représentés par la formule (I) dans laquelle R1-4, n et Ar correspondent aux définitions données dans la revendication 1, ainsi que les compositions pharmaceutiques correspondantes. Ces composés, qui sont des inhibiteurs de la tryptase, peuvent être utilisés pour le traitement de l'asthme et de maladies inflammatoires notamment.

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