C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 251/16 (2006.01) A61K 9/20 (2006.01) A61K 9/48 (2006.01) A61K 31/505 (2006.01) A61K 31/53 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) A61K 31/55 (2006.01) C07D 239/28 (2006.01) C07D 251/20 (2006.01) C07D 251/26 (2006.01) C07D 401/04 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 403/14 (2006.01) C07D 405/00 (2006.01) C07D 409/00 (2006.01) C07D 413/00 (2006.01) C07D 417/00 (2006.01) C07D 453/02 (2006.01) C07D 471/04 (2006.01) C07D 473/00 (2006.01) C07D 475/00 (2006.01)
Patent
CA 2249580
The present invention provides novel compounds, and pharmaceutical compositions thereof, and methods of using same in the treatment of affective disorders, anxiety, depression, post-traumatic stress disorders, eating disorders, supranuclear palsey, irritable bowl syndrome, immune supression, Alzheimer's disease, gastrointestinal diseases, anorexia nervosa, drug and alcohol withdrawal symptoms, drug addiction, inflammatory disorders, or fertility problems. The novel compounds provided by this invention are those of formula (I) wherein R1, R3, R5, Q, Z, Y, V, X and X' are as defined herein.
Nouveaux composés, compositions pharmaceutiques en dérivant et mode d'emploi de ceux-ci pour le traitement des troubles affectifs, de l'angoisse, de la dépression, du stress post-traumatique, des troubles alimentaires, de la paralysie supranucléaire, du syndrome du côlon irritable, de l'immunodépression, de la maladie d'Alzheimer, des affections gastro-intestinales, de l'anorexie nerveuse, des symptômes de sevrage des drogues et de l'alcool, de la toxicomanie, des troubles inflammatoires et des problèmes de fécondité. Les nouveaux composés qui font l'objet de la présente invention ont la formule (I) dans laquelle R?1¿, R?3¿, R?5¿, Q, Z, Y, V, X et X' sont définis dans la description.
Chorvat Robert J.
Rajagopalan Parthasarathi
Bristol-Myers Squibb Pharma Company
Dimock Stratton Llp
Du Pont Pharmaceuticals Company
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